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1

Precision medicine for metastatic breast cancer—limitations and solutions

Arnedos, Monica, Vicier, Cecile, Loi, Sherene, Lefebvre, Celine, Michiels, Stefan, Bonnefoi, Herve, Andre, Fabrice

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Year:

2015

Language:

english

File:

PDF, 461 KB

english, 2015

2

Activation of canonical BMP4-SMAD7 signaling suppresses breast cancer metastasis

Eckhardt, Bedrich L., Cao, Yuan, Redfern, Andrew D, Chi, Lap Hing, Burrows, Allan D, Roslan, Suraya, Sloan, Erica K., Parker, Belinda S., Loi, Sherene, Ueno, Naoto T., Lau, Peter K. H., Latham, Bruce,

Journal:

Cancer Research

Year:

2020

Language:

english

File:

PDF, 3.85 MB

english, 2020

3

Tissue-resident memory T cells in breast cancer control and immunotherapy responses

Byrne, Ann, Savas, Peter, Sant, Sneha, Li, Ran, Virassamy, Balaji, Luen, Stephen J., Beavis, Paul A., Mackay, Laura K., Neeson, Paul J., Loi, Sherene

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Year:

2020

Language:

english

File:

PDF, 1.47 MB

english, 2020

4

Clinical relevance of host immunity in breast cancer: from TILs to the clinic

Savas, Peter, Salgado, Roberto, Denkert, Carsten, Sotiriou, Christos, Darcy, Phillip K., Smyth, Mark J., Loi, Sherene

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Year:

2015

Language:

english

File:

PDF, 648 KB

english, 2015

5

Tumor-infiltrating lymphocytes in breast cancer and implications for clinical practice

de Melo Gagliato, Debora, Cortes, Javier, Curigliano, Giuseppe, Loi, Sherene, Denkert, Carsten, Perez-Garcia, Jose, Holgado, Esther

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Year:

2017

Language:

english

File:

PDF, 1.17 MB

english, 2017

6

Tissue-Dependent Tumor Microenvironments and Their Impact on Immunotherapy Responses

Oliver, Amanda J., Lau, Peter K. H., Unsworth, Ashleigh S., Loi, Sherene, Darcy, Phillip K., Kershaw, Michael H., Slaney, Clare Y.

Journal:

Frontiers in Immunology

Year:

2018

Language:

english

File:

PDF, 953 KB

english, 2018

7

In the beginning, there was chaos: A perspective on the development of immuno-oncological biomarkers

Salgado, Roberto, Harris, Lyndsay, Skvortsova, Ira, Denkert, Carsten, Loi, Sherene

Journal:

Seminars in Cancer Biology

Year:

2018

Language:

english

File:

PDF, 166 KB

english, 2018

8

The genetic landscape and clonal evolution of breast cancer resistance to palbociclib plus fulvestrant in the PALOMA-3 trial

O'Leary, Ben, Cutts, Rosalind J, Liu, Yuan, Hrebien, Sarah, Huang, Xin, Fenwick, Kerry, Andre, Fabrice, Loibl, Sibylle, Loi, Sherene, Garcia-Murillas, Isaac, Cristofanilli, Massimo, Huang Bartlett, Cy

Journal:

Cancer Discovery

Year:

2018

Language:

english

File:

PDF, 4.52 MB

english, 2018

9

Overall Survival with Palbociclib and Fulvestrant in Advanced Breast Cancer

Turner, Nicholas C., Slamon, Dennis J., Ro, Jungsil, Bondarenko, Igor, Im, Seock-Ah, Masuda, Norikazu, Colleoni, Marco, DeMichele, Angela, Loi, Sherene, Verma, Sunil, Iwata, Hiroji, Harbeck, Nadia, Lo

Journal:

New England Journal of Medicine

Year:

2018

Language:

english

File:

PDF, 381 KB

english, 2018

10

Securing the future of the clinician-scientist

Noble, Karen, Owens, Joanna, AndrÃ©, Fabrice, Bakhoum, Samuel F., Loi, Sherene, Reinhardt, Hans Christian, Tuveson, David, Swanton, Charles

Journal:

Year:

2020

Language:

english

File:

PDF, 783 KB

english, 2020

11

Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA): end-of-study results from a double-blind, randomised, placebo-controlled, phase 3 study

Swain, Sandra M, Miles, David, Kim, Sung-Bae, Im, Young-Hyuck, Im, Seock-Ah, Semiglazov, Vladimir, Ciruelos, Eva, Schneeweiss, Andreas, Loi, Sherene, Monturus, EstefanÃa, Clark, Emma, Knott, Adam, Re

Journal:

The Lancet Oncology

Year:

2020

File:

PDF, 396 KB

2020

12

The use of gene-expression profiling to better understand the clinical heterogeneity of estrogen receptor positive breast cancers and tamoxifen response

Sherene Loi, Martine Piccart, Christos Sotiriou

Journal:

Critical Reviews in Oncology/Hematology

Year:

2007

Language:

english

File:

PDF, 136 KB

english, 2007

13

Gene expression profiling identifies activated growth factor signaling in poor prognosis (Luminal-B) estrogen receptor positive breast cancer

Sherene Loi, Christos Sotiriou, Benjamin Haibe-Kains, Francoise Lallemand, Nelly M Conus, Martine J Piccart, Terence P Speed, Grant A McArthur

Journal:

BMC Medical Genomics

Year:

2009

Language:

english

File:

PDF, 886 KB

english, 2009

14

A randomized cross-over trial to determine the effect of Cremophor EL on the pharmacodynamics and pharmacokinetics of carboplatin chemotherapy

Sherene Loi, Danny Rischin, Michael Michael, Kally Yuen, Kerrie H. Stokes, Andrew G. Ellis, Michael J. Millward, Lorraine K. Webster

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2004

Language:

english

File:

PDF, 240 KB

english, 2004

15

Time to move forward from “first-generation” prognostic gene signatures in early breast cancer

Christine Desmedt, Stefan Michiels, Benjamin Haibe-Kains, Sherene Loi, Christos Sotiriou

Journal:

Breast Cancer Research and Treatment

Year:

2011

Language:

english

File:

PDF, 120 KB

english, 2011

16

Glomerulosclerosis: A paraneoplastic phenomenon? : Case Report

SHERENE LOI, GREGORY J PERRY, HUGO STANDISH, JOHN DOWLING

Journal:

Year:

2004

Language:

english

File:

PDF, 182 KB

english, 2004

17

Beyond trastuzumab: New treatment options for HER2-positive breast cancer

Kamal S. Saini, Hatem A. Azim Jr, Otto Metzger-Filho, Sherene Loi, Christos Sotiriou, Evandro de Azambuja, Martine Piccart

Journal:

Year:

2011

Language:

english

File:

PDF, 255 KB

english, 2011

18

Prediction of breast cancer prognosis using gene set statistics provides signature stability and biological context

Gad Abraham, Adam Kowalczyk, Sherene Loi, Izhak Haviv, Justin Zobel

Journal:

BMC Bioinformatics

Year:

2010

Language:

english

File:

PDF, 1.20 MB

english, 2010

19

Predicting prognosis using molecular profiling in estrogen receptor-positive breast cancer treated with tamoxifen

Sherene Loi, Benjamin Haibe-Kains, Christine Desmedt, Pratyaksha Wirapati, Françoise Lallemand, Andrew M Tutt, Cheryl Gillet, Paul Ellis, Kenneth Ryder, James F Reid, Maria G Daidone, Marco A Pierotti

Journal:

Year:

2008

Language:

english

File:

PDF, 464 KB

english, 2008

20

Molecular analysis of hormone receptor positive (luminal) breast cancers – What have we learnt?

Journal:

European Journal of Cancer

Year:

2008

Language:

english

File:

PDF, 125 KB

english, 2008

21

Incidence of Malignancies in Heart and/or Lung Transplant Recipients: A Single-Institution Experience

Sabine Roithmaier, Andrew M. Haydon, Sherene Loi, Don Esmore, Ann Griffiths, Peter Bergin, Trevor J. Williams, Max A. Schwarz

Journal:

The Journal of Heart and Lung Transplantation

Year:

2007

Language:

english

File:

PDF, 156 KB

english, 2007

22

Proposals for uniform collection of biospecimens from neoadjuvant breast cancer clinical trials: timing and specimen types

Sherene Loi, W Fraser Symmans, John MS Bartlett, Debora Fumagalli, Laura Van't Veer, John F Forbes, Philippe Bedard, Carsten Denkert, JoAnne Zujewski, Giuseppe Viale, Lajos Pusztai, Laura J Esserman,

Journal:

The Lancet Oncology

Year:

2011

Language:

english

File:

PDF, 121 KB

english, 2011

23

A common language in neoadjuvant breast cancer clinical trials: proposals for standard definitions and endpoints

Debora Fumagalli, Philippe L Bedard, Zeina Nahleh, Stefan Michiels, Christos Sotiriou, Sherene Loi, Joseph A Sparano, Matthew Ellis, Nola Hylton, Jo Anne Zujewski, Clifford Hudis, Laura Esserman, Mart

Journal:

The Lancet Oncology

Year:

2012

Language:

english

File:

PDF, 144 KB

english, 2012

24

Targeting the PI3K/AKT/mTOR and Raf/MEK/ERK pathways in the treatment of breast cancer

Saini, Kamal S., Loi, Sherene, de Azambuja, Evandro, Metzger-Filho, Otto, Saini, Monika Lamba, Ignatiadis, Michail, Dancey, Janet E., Piccart-Gebhart, Martine J.

Journal:

Cancer Treatment Reviews

Year:

2013

Language:

english

File:

PDF, 924 KB

english, 2013

25

Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape

Bidwell, Bradley N, Slaney, Clare Y, Withana, Nimali P, Forster, Sam, Cao, Yuan, Loi, Sherene, Andrews, Daniel, Mikeska, Thomas, Mangan, Niamh E, Samarajiwa, Shamith A, de Weerd, Nicole A, Gould, Jode

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 1.77 MB

english, 2012

26

Evidence-Based Adjuvant Treatment of Resectable Pancreatic Adenocarcinoma

Dr Sherene Loi, Michael Findlay, John Zalcberg

Journal:

American Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 120 KB

english, 2005

27

Foreword

Bozovic-Spasojevic, Ivana, Ameye, Lieveke, Paesmans, Marianne, Larsimont, Denis, Di Leo, Angelo, Dolci, Stella, Piccart, Martine, de Azambuja, Evandro, Loi, Sherene

Journal:

Zeitschrift für Pflanzenphysiologie

Year:

1984

File:

PDF, 67 KB

1984

28

Announcements and notices

Bozovic-Spasojevic, Ivana, Ameye, Lieveke, Paesmans, Marianne, Larsimont, Denis, Di Leo, Angelo, Dolci, Stella, Piccart, Martine, de Azambuja, Evandro, Loi, Sherene

Journal:

The American Journal of Emergency Medicine

Year:

1990

Language:

english

File:

PDF, 89 KB

english, 1990

29

Prognostic, predictive abilities and concordance of BCL2 and TP53 protein expression in primary breast cancers and axillary lymph-nodes: A retrospective analysis of the Belgian three arm study evaluating anthracycline vs CMF adjuvant chemotherapy

Bozovic-Spasojevic, Ivana, Ameye, Lieveke, Paesmans, Marianne, Larsimont, Denis, Di Leo, Angelo, Dolci, Stella, Piccart, Martine, de Azambuja, Evandro, Loi, Sherene

Journal:

Year:

2014

Language:

english

File:

PDF, 1.08 MB

english, 2014

30

Investigating the positive relationship between tumor-infiltrating lymphocytes and trastuzumab therapy

Savas, Peter, Loi, Sherene

Journal:

Year:

2014

Language:

english

File:

PDF, 1.61 MB

english, 2014

31

Gene signature evaluation as a prognostic tool: challenges in the design of the MINDACT trial

Bogaerts, Jan, Cardoso, Fatima, Buyse, Marc, Braga, Sofia, Loi, Sherene, Harrison, Jillian A, Bines, Jacques, Mook, Stella, Decker, Nuria, Ravdin, Peter, Therasse, Patrick, Rutgers, Emiel, van 't Veer

Journal:

Nature Clinical Practice Oncology

Year:

2006

Language:

english

File:

PDF, 253 KB

english, 2006

32

Oncogene addiction and immunity

Savas, Peter, Caramia, Franco, Teo, Zhi Ling, Loi, Sherene

Journal:

Current Opinion in Oncology

Year:

2014

Language:

english

File:

PDF, 245 KB

english, 2014

33

PIK3CAmutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor—positive breast cancer

Sherene Loi, Benjamin Haibe-Kains, Samira Majjaj, Francoise Lallemand, Virginie Durbecq, Denis Larsimont, Ana M. Gonzalez-Angulo, Lajos Pusztai, W. Fraser Symmans, Alberto Bardelli, Paul Ellis, Andrew

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.55 MB

english, 2010

34

Tumor-infiltrating lymphocytes, breast cancer subtypes and therapeutic efficacy

Journal:

Year:

2013

Language:

english

File:

PDF, 594 KB

english, 2013

35

Tumour-Infiltrating Lymphocytes (TILs) in Breast Cancer: a Predictive or a Prognostic Marker?

Dushyanthen, Sathana, Savas, Peter, Willard-Gallo, Karen, Denkert, Carsten, Salgado, Roberto, Loi, Sherene

Journal:

Current Breast Cancer Reports

Year:

2015

Language:

english

File:

PDF, 6.38 MB

english, 2015

36

Research Resource: Nuclear Receptors as Transcriptome: Discriminant and Prognostic Value in Breast Cancer

Muscat, George E. O., Eriksson, Natalie A., Byth, Karen, Loi, Sherene, Graham, Dinny, Jindal, Shalini, Davis, Melissa J., Clyne, Colin, Funder, John W., Simpson, Evan R., Ragan, Mark A., Kuczek, Eliza

Journal:

Molecular Endocrinology

Year:

2013

Language:

english

File:

PDF, 1024 KB

english, 2013

37

Phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway inhibition

Zardavas, Dimitrios, Fumagalli, Debora, Loi, Sherene

Journal:

Current Opinion in Oncology

Year:

2012

Language:

english

File:

PDF, 262 KB

english, 2012

38

RANK-ligand (RANKL) expression in young breast cancer patients and during pregnancy

Azim, Hatem A, Peccatori, Fedro A, Brohée, Sylvain, Branstetter, Daniel, Loi, Sherene, Viale, Giuseppe, Piccart, Martine, Dougall, William C, Pruneri, Giancarlo, Sotiriou, Christos

Journal:

Breast Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.46 MB

english, 2015

39

Tumour infiltrating lymphocytes (TILs) in breast cancer during pregnancy

Azim, Hatem A., Vingiani, Andrea, Peccatori, Fedro, Viale, Giuseppe, Loi, Sherene, Pruneri, Giancarlo

Journal:

Year:

2015

Language:

english

File:

PDF, 421 KB

english, 2015

40

Palbociclib in Hormone-Receptor–Positive Advanced Breast Cancer

Turner, Nicholas C., Ro, Jungsil, André, Fabrice, Loi, Sherene, Verma, Sunil, Iwata, Hiroji, Harbeck, Nadia, Loibl, Sibylle, Huang Bartlett, Cynthia, Zhang, Ke, Giorgetti, Carla, Randolph, Sophia, Koe

Journal:

New England Journal of Medicine

Year:

2015

Language:

english

File:

PDF, 274 KB

english, 2015

41

PIK3CAmutations in breast cancer: reconciling findings from preclinical and clinical data

Zardavas, Dimitrios, Phillips, Wayne A, Loi, Sherene

Journal:

Breast Cancer Research

Year:

2014

Language:

english

File:

PDF, 765 KB

english, 2014

42

A network meta-analysis of everolimus plus exemestane versus chemotherapy in the first- and second-line treatment of estrogen receptor-positive metastatic breast cancer

Generali, Daniele, Venturini, Sergio, Rognoni, Carla, Ciani, Oriana, Pusztai, Lajos, Loi, Sherene, Jerusalem, Guy, Bottini, Alberto, Tarricone, Rosanna

Journal:

Breast Cancer Research and Treatment

Year:

2015

Language:

english

File:

PDF, 761 KB

english, 2015

43

CD73: A potential biomarker for anti-PD-1 therapy

Beavis, Paul A, Slaney, Clare Y, Milenkovski, Nicole, Henderson, Melissa A, Loi, Sherene, Stagg, John, Kershaw, Michael H, Darcy, Phillip K

Journal:

Year:

2015

Language:

english

File:

PDF, 631 KB

english, 2015

44

Immunity and HER2-positive disease: never stop questioning

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 287 KB

english, 2015

45

Relevance of tumor-infiltrating lymphocytes in breast cancer

Dushyanthen, Sathana, Beavis, Paul A., Savas, Peter, Teo, Zhi Ling, Zhou, Chenhao, Mansour, Mariam, Darcy, Phillip K., Loi, Sherene

Journal:

Year:

2015

Language:

english

File:

PDF, 2.35 MB

english, 2015

46

Breast cancer gene expression profiling: clinical trial and practice implications

Loi, Sherene, Desmedt, Christine, Cardoso, Fatima, Piccart, Martine, Sotiriou, Christos

Journal:

Pharmacogenomics

Year:

2005

Language:

english

File:

PDF, 100 KB

english, 2005

47

Molecular segmentation of luminal breast: Reality in 2015?

Teo, Zhi Ling, Loi, Sherene

Journal:

Year:

2015

Language:

english

File:

PDF, 216 KB

english, 2015

48

Immunomodulation via Chemotherapy and Targeted Therapy: A New Paradigm in Breast Cancer Therapy?

Stagg, John, Andre, Fabrice, Loi, Sherene

Journal:

Year:

2012

Language:

english

File:

PDF, 273 KB

english, 2012

49

Fulvestrant plus palbociclib versus fulvestrant plus placebo for treatment of hormone-receptor-positive, HER2-negative metastatic breast cancer that progressed on previous endocrine therapy (PALOMA-3): final analysis of the multicentre, double-blind, phase 3 randomised controlled trial

Cristofanilli, Massimo, Turner, Nicholas C, Bondarenko, Igor, Ro, Jungsil, Im, Seock-Ah, Masuda, Norikazu, Colleoni, Marco, DeMichele, Angela, Loi, Sherene, Verma, Sunil, Iwata, Hiroji, Harbeck, Nadia

Journal:

The Lancet Oncology

Year:

2016

Language:

english

File:

PDF, 639 KB

english, 2016

50

Effects of Estrogen Receptor and Human Epidermal Growth Factor Receptor-2 Levels on the Efficacy of Trastuzumab

Loi, Sherene, Dafni, Urania, Karlis, Dimitris, Polydoropoulou, Varvara, Young, Brandon M., Willis, Scooter, Long, Bradley, de Azambuja, Evandro, Sotiriou, Christos, Viale, Giuseppe, Rüschoff, Josef, P

Journal:

Year:

2016

Language:

english

File:

PDF, 494 KB

english, 2016

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